Iron loading with ferrocene dysregulates iron homeostasis in an organotypic hippocampal slice culture model
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چکیده
منابع مشابه
Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model
Aberrant iron deposition in the brain is associated with neurodegenerative disorders including Multiple Sclerosis, Alzheimer's disease and Parkinson's disease. To study the collective response to iron loading, we have used hippocampal organotypic slices as a platform to develop a novel ex vivo model of iron accumulation. We demonstrated differential uptake and toxicity of iron after 12 h exposu...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2014
ISSN: 1662-453X
DOI: 10.3389/conf.fnins.2014.87.00034